Dr. Montgomery was part of the team that developed the laparoscopic procedure for live kidney donation, a procedure that has become the standard throughout the world. He and the Hopkins team conceived the idea of the Domino Paired Donation (kidney swaps), the Hopkins protocol for desensitization of incompatible kidney transplant patients, and performed the first chain of transplants started by an altruistic donor. He led the team that performed the first 2-way domino paired donation, 3-way paired donation, 3-way domino paired donation, 4-way paired donation, 4-way domino paired donation, 5-way domino paired donation, 6-way domino paired donation, 8-way multi-institutional domino paired donation, and co-led the first 10-way open chain. He is credited in the 2010 Guinness Book of World Records with the most kidney transplants performed in 1 day. He is considered a world expert on kidney transplantation for highly sensitized and ABO incompatible patients and is referred the most complex patients from around the globe.
Dr. Montgomery has had clinical and basic science research supported by the NIH throughout his career. His academic interests include HLA sensitization, tolerance protocols including simultaneous solid organ and bone marrow transplantation, and xenotransplantation. He has received important awards and distinctions including a Fulbright Scholarship and a Thomas J. Watson Fellowship and memberships in the Phi Beta Kappa and Alpha Omega Alpha academic honor societies. He has been awarded multiple scholarships from The American College of Surgeons and The American Society of Transplant Surgeons. The National Kidney Foundation of Maryland has recognized his contributions to the field of transplantation with the Champion of Hope Award, the National Kidney Registry with the Terasaki Medical Innovation Award and The Greater New York Hospital Association with the Profile in Courage Award. In 2018, he became a recipient of a heart transplant from a Hepatitis C positive donor and has worked to try to promote this practice throughout the world.