Desensitization against blood group antibodies is relatively easy and has little impact on graft survival, whereas anti-HLA antibodies are difficult to desensitize and have a negative impact on graft survival due to the increased risk of AMR. One possible cause of this is accommodation, which is defined as the absence of AMR despite the presence of antibody production in the body. However, the molecular mechanism of accommodation to anti-blood group and anti-HLA antibodies remains unclear.
“This Masterclass has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 1 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.”Attendance to the live Masterclass and the completion of the post-event survey are mandatory to receive the certificate and CME credits.
“Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at www.ama-assn.org/education/earn-credit-participation-international-activities.
“Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.”
Welcome and introduction by the Chairs
Presentation: Different approach in immunosuppression to ABO and HLA-incompatible organ Transplantation, Robert Montgomery, USA
Presentation: Molecular mechanisms of accommodation in ABO- and HLA-incompatible organ Transplantation, Hideki Ohdan, Japan
Interactive panel discussion with audience participation led by the Chairs
Masterclass closing remarks