HLA matching plays of vital importance in transplantation because mismatches of HLA alleles possibly evoke both cellular and antibody-mediated rejection. As such, it would be ideally plausible if we can only transplant organs with zero HLA mismatch. However, with a shortage of organs, the use of mismatched organs became essential. The introduction of potent immunosuppressive agents for both induction and maintenance therapy helped controlling cellular rejection but not humoral mediated rejection (AMR), which is strongly correlated with donor-specific anti-HLA antibodies (DSA), resulting in a poor outcome. We have Dr. Zafar with vast experience in transplanting living related patients with the best HLA matching and Dr. Asker, who will present the impact of HLA in the diseased transplant program.
“This Masterclass has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 1 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.”Attendance to the live Masterclass and the completion of the post-event survey are mandatory to receive the certificate and CME credits.
“Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at www.ama-assn.org/education/earn-credit-participation-international-activities.
“Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.”
Presentation:Outcome with HLA matching results in deceased renal transplant, Medhat Askar, USA
Live Q&A with Medhat Askar, USA
Presentation: Outcome with HLA matching in living renal transplant, Mirza Naqi Zafar, Pakistan
Live Q&A with Mirza Naqi Zafar, Pakistan
Masterclass closing remarks