Personalized immunosuppression dosing algorithms
Marith Francke
Erasmus MC, University Medical Center Rotterdam
Department of Internal Medicine
Division of Nephrology and Transplantation
The Netherlands
Marith Francke (1997) is a Ph.D. student at the department of internal medicine, division of nephrology and transplantation at the Erasmus MC, University Medical Center Rotterdam, the Netherlands. In 2015 she started her Bachelors in Medicine, followed by a research master in Clinical research. Currently, she is employed as a Ph.D. student. Her research focuses on the optimization of immunosuppressive therapy after kidney transplantation. She works on strategies to improve tacrolimus treatment and she tries to explain variability in the pharmacokinetics of the drug and to use dosing algorithms for tacrolimus to predict an individual’s dose requirement. The overarching aim is to further personalize tacrolimus treatment after transplantation.
An overarching approach to personalized immunosuppression
David Axelrod
Professor of Surgery
Surgical Director of Kidney, Pancreas, and Living Donor Transplantation Fellowship Director
University of Iowa
Iowa City, USA
Dr. Axelrod is currently Professor of Surgery at the University of Iowa. He serves as the Surgical Director of Kidney, Pancreas, and Living Donor Transplantation and fellowship director. He previously was Section Chief of Solid Organ Transplantation at Dartmouth Hitchcock Medical Center from 2005-16. In addition, he was a member of the clinical staff at Massachusetts General Hospital and subsequently at Lahey Hospital. His clinical interests include the surgical management of end-stage kidney and liver disease including treatment of hepatocellular carcinoma and portal hypertension.
His research interests including surgical outcomes analysis including economic evaluation, Markov modeling, and statistical process control techniques. Previous investigations have examined the economic impact of MELD on liver transplantation, quality outcome monitoring in organ transplantation, steroid-free immunosuppression in kidney and pancreas transplants, and geographic disparities in access to organ transplant.
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