This masterclass will discuss the most up-to-date knowledge on the epidemiology, clinical presentation, and immune responses to Polyomavirus infection in kidney transplant recipients. Recent data on the potential therapies for Polyomaviruses in kidney transplantation will also be presented.
Learning Objectives:
Understand the immunology, epidemiology, and clinical presentation of polyomavirus in kidney transplant recipients
Learn the latest advances in screening, detection, and treatment strategies of polyomavirus in kidney transplant recipients
Faculty:
BK polyomavirus: clinical aspects and immune regulation
Hans Hirsch
Director of the Clinical Virology Diagnostic Laboratory University of Basel Consultant Infectious Diseases & Hospital Epidemiology University Hospital Basel Basel, Switzerland
Hans H. Hirsch, MD, MSc, studied medicine at the Albert-Ludwigs-University in Freiburg (Germany) and biochemistry at Oregon State University in Corvallis (OR, USA). He then specialized in internal medicine, infectious diseases, and medical microbiology at the University of Basel and the University Hospital Basel. In 2004, the Medical Faculty of the University of Basel appointed him as Professor for Medical Microbiology. Currently, Dr. Hirsch is the director of the Clinical Virology diagnostic laboratory and holds a senior clinical appointment as a consultant in Infectious Diseases at the University Hospital Basel. Dr. Hirsch heads the research group “Transplantation & Clinical Virology” at the Department of Biomedicine of the University of Basel. Dr. Hirsch has a special interest in virus infections and immunocompromised patients, including transplant and HIV patients, and is a member of the Swiss HIV Cohort Study, the Swiss Transplant Cohort Study. Dr. Hirsch was engaged as TTS-Transplant Infectious Disease Councilor for Africa-Europe-Middle East (2015 – 2017) and is Fellow of European Society Clinical Microbiology & Infectious Diseases (ESCMID), Fellow of the American Society of Transplantation (FAST), and the current president of the International Immunocompromised Host Society (ICHS).
BK polyomavirus: emerging therapies
Brian Nankivell
Transplant Physician, Dept Renal Medicine Westmead Hospital Sydney, Australia
Dr. Nankivell is currently a practicing nephrologist and transplant clinician working at Westmead Hospital and the National Pancreas Transplant Unit in Sydney.
His MBBS was from the University of Sydney. Following his FRACP, specializing in nephrology, an MSc in pharmacology from the University of London, and two doctorates from the University of Sydney were obtained; as a Ph.D. in the mechanisms of progression of chronic renal failure and a higher doctorate MD examining transplant graft dysfunction.
His research interests involve transplant renal function, the structural-functional relationships of failing allografts, renal function estimation, the histopathology of acute and chronic transplant rejection, calcineurin inhibitor nephrotoxicity, BK virus allograft nephropathy, and the Banff schema of diagnostic transplant pathology.
Chairs
Helen Pilmore
Associate Professor Auckland University and Auckland City Hospital Aukland, New Zealand
John Kanelis
Head of Transplantation Monash Medical Centre Melbourne, Australia
Schedule (90 min):
05 min
Welcome and introduction by the Chairs
25 min
Presentation: BK polyomavirus: clinical aspects and immune regulation, Hans Hirsch, Switzerland
05 min
Live Q&A with Hans Hirsch, Switzerland
25 min
Presentation: BK polyomavirus: emerging therapies, Brian Nankivell, Australia
05 min
Live Q&A with Brian Nankivell, Australia
20 min
Interactive panel discussion with audience participation led by the Chairs